Product Name :
Edoxaban
Description:
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non–central-nervous-system systemic embolism.
CAS:
480449-70-5
Molecular Weight:
548.06
Formula:
C24H30ClN7O4S
Chemical Name:
N’-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]ethanediamide
Smiles :
CN(C)C(=O)[C@@H]1C[C@@H](NC(=O)C2=NC3CCN(C)CC=3S2)[C@H](CC1)NC(=O)C(=O)NC1=CC=C(Cl)C=N1
InChiKey:
HGVDHZBSSITLCT-JLJPHGGASA-N
InChi :
InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery.{{Sumatriptan} web|{Sumatriptan} 5-HT Receptor|{Sumatriptan} Technical Information|{Sumatriptan} In Vivo|{Sumatriptan} custom synthesis|{Sumatriptan} Autophagy} It was also approved by the FDA in January 2015 for the prevention of stroke and non–central-nervous-system systemic embolism.|Product information|CAS Number: 480449-70-5|Molecular Weight: 548.06|Formula: C24H30ClN7O4S|Chemical Name: N’-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-amido}cyclohexyl]ethanediamide|Smiles: CN(C)C(=O)[C@@H]1C[C@@H](NC(=O)C2=NC3CCN(C)CC=3S2)[C@H](CC1)NC(=O)C(=O)NC1=CC=C(Cl)C=N1|InChiKey: HGVDHZBSSITLCT-JLJPHGGASA-N|InChi: InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Sitagliptin} site|{Sitagliptin} Dipeptidyl Peptidase|{Sitagliptin} Biological Activity|{Sitagliptin} Formula|{Sitagliptin} supplier|{Sitagliptin} Cancer} |Shelf Life: ≥360 days if stored properly.PMID:23614016 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
