anti-slc16a1 rabbit mab

Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-SLC16A1 Rabbit mAb Clone Number: JRMR-11100-20 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB IHC-P Reactivity: Human, Rat Synonyms: Monocarboxylate transporter 1, Solute carrier family 16 member 1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms Monocarboxylate transporter 1, Solute carrier family 16 member 1 UniProt ID P53985 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 Human IHC-P 1:500 – 1:1000 Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background MCT1, also known as MOT1, is a multi-pass transmembrane monocarboxylate transporter (MCT) protein, encoded by the gene SLC16A1. MCT1 is reported to be expressed in multiple tissues and cell types, including erythrocytes, immune cells, and both cardiac and skeletal myocytes. The primary role of MCT1 is to facilitate proton-coupled transport of monocarboxlates (e.g., lactate, pyruvate, ketone bodies) across the plasma membrane in response to cellular metabolic demands. The regulation of monocarboxylate flux by MCT1 has been identified as a possible metabolic biomarker in various diseases, including neurodegenerative diseases, ischemia, and cancer. Inhibition of MCT1 has thus been proposed as a potential therapeutic treatment of cancer Cellular location Cell membrane Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1: 1000 Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: Jurkat; 2: SK-BR-3; 3: HT-29; 4: Human heart Protein loading amount: 20 μg Exposure time: 60 secondsPredicted band size: 54 kDa Observed band size: 54 kDa IHC-P Tissue: Rat colon Section type: Formalin-fixed & paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH9.0 Primary Ab dilution: 1:500 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with :
Recombinant Rabbit Monoclonal Anti-SLC16A1 Rabbit mAb Clone Number: JRMR-11100-20 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB IHC-P Reactivity: Human, Rat Synonyms: Monocarboxylate transporter 1, Solute carrier family 16 member 1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms Monocarboxylate transporter 1, Solute carrier family 16 member 1 UniProt ID P53985 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 Human IHC-P 1:500 – 1:1000 Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background MCT1, also known as MOT1, is a multi-pass transmembrane monocarboxylate transporter (MCT) protein, encoded by the gene SLC16A1. MCT1 is reported to be expressed in multiple tissues and cell types, including erythrocytes, immune cells, and both cardiac and skeletal myocytes. The primary role of MCT1 is to facilitate proton-coupled transport of monocarboxlates (e.g., lactate, pyruvate, ketone bodies) across the plasma membrane in response to cellular metabolic demands. The regulation of monocarboxylate flux by MCT1 has been identified as a possible metabolic biomarker in various diseases, including neurodegenerative diseases, ischemia, and cancer. Inhibition of MCT1 has thus been proposed as a potential therapeutic treatment of cancer Cellular location Cell membrane Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1: 1000 Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: Jurkat; 2: SK-BR-3; 3: HT-29; 4: Human heart Protein loading amount: 20 μg Exposure time: 60 secondsPredicted band size: 54 kDa Observed band size: 54 kDa IHC-P Tissue: Rat colon Section type: Formalin-fixed & paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH9.0 Primary Ab dilution: 1:500 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with