anti-prame rabbit mab

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Recombinant Rabbit Monoclonal Anti-PRAME Rabbit mAb Clone Number: JRMR-10891-30 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human Synonyms: MAPE, OIP4 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms MAPE, OIP4 UniProt ID P78395 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background PRAME (preferentially expressed antigen in melanoma) is a cancer/testis antigen not normally expressed in any tissues except testis. PRAME is expressed in melanoma cells and is recognized by cytolytic T-cells. It is also upregulated in other diseases, such as synovial sarcoma, NSCLC, and breast cancer, where it is thought to contribute to tumorigenesis and metastasis. PRAME is also highly expressed in liquid tumors such as AML and can be predictive of clinical outcome in some circumstances. PRAME and other cancer/testis antigens are currently being pursued as novel immunotherapy targets and diagnostic biomarkers Cellular location Membrane, Cytoplasm, Golgi apparatus, Nucleus Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 4℃ overnight Secondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate) Lysate: 1: Ramos, 2: K562, 3: HeLa, 4: A375 Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 58 kDa Observed band size: 58 kDa :
Recombinant Rabbit Monoclonal Anti-PRAME Rabbit mAb Clone Number: JRMR-10891-30 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human Synonyms: MAPE, OIP4 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms MAPE, OIP4 UniProt ID P78395 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background PRAME (preferentially expressed antigen in melanoma) is a cancer/testis antigen not normally expressed in any tissues except testis. PRAME is expressed in melanoma cells and is recognized by cytolytic T-cells. It is also upregulated in other diseases, such as synovial sarcoma, NSCLC, and breast cancer, where it is thought to contribute to tumorigenesis and metastasis. PRAME is also highly expressed in liquid tumors such as AML and can be predictive of clinical outcome in some circumstances. PRAME and other cancer/testis antigens are currently being pursued as novel immunotherapy targets and diagnostic biomarkers Cellular location Membrane, Cytoplasm, Golgi apparatus, Nucleus Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 4℃ overnight Secondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate) Lysate: 1: Ramos, 2: K562, 3: HeLa, 4: A375 Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 58 kDa Observed band size: 58 kDa