Product Name: Activin Receptor IIB Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant extracellular domain (ecd) of mouse activin receptor IIB.
Host Species: Rabbit
Purification: Antigen affinity purified.
Physical State: Liquid
CAS NO.: 1821908-48-8
Product: SGC2085
Buffer: Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide.
Concentration: 500 ug/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ACVR2B; ACTR-IIB; Activin receptor type-2B
Accession NO.: P27040
Protein Ino: 114727
Official Symbol: Acvr2b
Geneid: 11481
Background: Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.
PubMed ID:http://aac.asm.org/content/52/3/1080.abstract
