Product Name: ACOT11 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 68 kDa
Immunogen: This ACOT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-575 amino acids from the C-terminal region of human ACOT11.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1233855-46-3
Product: BIA 10-2474
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, 312-, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, ACOT11, BFIT, KIAA0707, THEA
Accession NO.: Q8WXI4
Protein Ino: 21363000
Official Symbol: ACOT11
Geneid: 26027
Background: This gene encodes a member of the acyl-CoA thioesterasefamily which catalyse the conversion of activated fatty acids tothe corresponding non-esterified fatty acid and coenzyme A.Expression of a mouse homolog in brown adipose tissue is induced bylow temperatures and repressed by warm temperatures. Higher levelsof expression of the mouse homolog has been found inobesity-resistant mice compared with obesity-prone mice, suggestinga role of acyl-CoA thioesterase 11 in obesity. Alternative splicingresults in transcript variants.
PubMed ID:http://aac.asm.org/content/52/2/598.abstract
