Product Name: ACK1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 115 kDa
Immunogen: This ACK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-290 amino acids from the Central region of human ACK1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 692737-80-7
Product: Dovitinib (lactate)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.35 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Activated CDC42 kinase 1, ACK-1, Tyrosine kinase non-receptor protein 2, TNK2, ACK1
Accession NO.: Q07912
Protein Ino: 229462980
Official Symbol: TNK2
Geneid: 10188
Background: This gene encodes a tyrosine kinase that binds Cdc42Hs inits GTP-bound form and inhibits both the intrinsic andGTPase-activating protein (GAP)-stimulated GTPase activity ofCdc42Hs. This binding is mediated by a unique sequence of 47 aminoacids C-terminal to an SH3 domain. The protein may be involved in aregulatory mechanism that sustains the GTP-bound active form ofCdc42Hs and which is directly linked to a tyrosine phosphorylationsignal transduction pathway. Several alternatively splicedtranscript variants have been identified from this gene, but thefull-length nature of only two transcript variants has beendetermined.
PubMed ID:http://aac.asm.org/content/52/2/491.abstract
