Product Name: ACF Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 65 kDa
Immunogen: This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 526-18-1
Product: Osalmid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: APOBEC1 complementation factor, APOBEC1-stimulating protein, A1CF, ACF, ASP {ECO:0000312|EMBL:CAB947541}
Accession NO.: Q9NQ94
Protein Ino: 74761651
Official Symbol: A1CF
Geneid: 29974
Background: Mammalian apolipoprotein B mRNA undergoes site-specific Cto U deamination, which is mediated by a multi-component enzymecomplex containing a minimal core composed of APOBEC-1 and acomplementation factor encoded by this gene. The gene product hasthree non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that thiscomplementation factor functions as an RNA-binding subunit anddocks APOBEC-1 to deaminate the upstream cytidine. Studies suggestthat the protein may also be involved in other RNA editing or RNAprocessing events.
PubMed ID:http://aac.asm.org/content/52/1/220.abstract
