anti-il-4r mouse mab

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Recombinant Anti-IL-4R Mouse mAb This item is discontinued. Please see alternative products below. Clone Number: 11733 Host: Mouse Clonality: Recombinant Monoclonal Applications： ICC/IF FC Reactivity: Human Synonyms: IL4RA Product Size 100 μl Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2a/kappa Conjugate Unconjugated Synonyms IL4RA UniProt ID P24394 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species ICC/IF 1:50 Human FC 1:50 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3 -STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/ IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells. Cellular location Membrane, Secreted Images ICC/IF Cell line: A431 Fixative: 100% Ice-cold methanol Permeabilization: 0.1% Triton X-100 Primary Ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary Ab: Goat Anti-Mouse IgGNuclear counter stain: DAPI (Blue) Description: The green color represents the positive signal observed with :
Recombinant Anti-IL-4R Mouse mAb This item is discontinued. Please see alternative products below. Clone Number: 11733 Host: Mouse Clonality: Recombinant Monoclonal Applications： ICC/IF FC Reactivity: Human Synonyms: IL4RA Product Size 100 μl Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2a/kappa Conjugate Unconjugated Synonyms IL4RA UniProt ID P24394 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species ICC/IF 1:50 Human FC 1:50 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3 -STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/ IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells. Cellular location Membrane, Secreted Images ICC/IF Cell line: A431 Fixative: 100% Ice-cold methanol Permeabilization: 0.1% Triton X-100 Primary Ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary Ab: Goat Anti-Mouse IgGNuclear counter stain: DAPI (Blue) Description: The green color represents the positive signal observed with