Product Name: ABL2 Antibody [1H1B11]
Species Reactivity: Human
Tested Applications: ELISA, IF, WB
Applications: DilutionWestern Blot:1:200 – 1:1,000 IF:1:100 – 1:500ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified truncated recombinant ABL2 expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification:
Physical State:
CAS NO.: 87-51-4
Product: 3-Indoleacetic acid
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration:
Storage Conditions: ABL2 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: ABLL, ARG, Abelson murine leukemia viral oncogene homolog 2ARG, ABLL
Accession NO.: P42684
Protein Ino: 1168268
Official Symbol: ABL2
Geneid: 27
Background: ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization，c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.
PubMed ID:http://aac.asm.org/content/51/12/4342.abstract
