A, Roncador A, Cellini B, Hughes RM, Tucker CL: Rapid profiling of disease alleles employing a tunable reporter of protein misfolding. Genetics 2012, 192:83142. 41. Daidone F, Montioli R, Paiardini A, Cellini B, Macchiarulo A, Giardina G, Bossa F, Borri Voltattorni C: Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. PLoS 1 2012, 7:e31610. 42. Daidone F, Florio R, Rinaldo S, Contestabile R, di Salvo ML, CutruzzolF, Bossa F, Paiardini A: In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target from the antifolate drug pemetrexed. Eur J Med Chem 2011, 46:1616621. 43. Punta M, Coggill Computer, Eberhardt RY, Mistry J, Tate J, Boursnell C, Pang N, Forslund K, Ceric G, Clements J, Heger A, Holm L, Sonnhammer EL, Eddy SR, Bateman A, Finn RD: The Pfam protein households database. Nucleic Acids Res 2012, 40:D290 301. 44. Schuenke KW, Walker DH: Cloning sequencing and expression of the gene coding for an antigenic 120kilodalton protein of Rickettsia conorii. Infect Immun 1994, 162:90409. 45. Kohm AP, Fuller KG, Miller SD: Mimicking the strategy to autoimmunity: an evolving theory of sequence and structural homology. Trends Microbiol 2003, 11:10105. 46. Ma Y, Okamoto M, Thomas MG, Bogdanos DP, Lopes AR, Portmann B, Underhill J, D r R, Mieli-Vergani G, Vergani D: Antibodies to conformational epitopes of soluble liver antigen define a severe kind of autoimmune liver illness. Hepatology 2002, 35:65864. 47. Araiso Y, Palioura S, Ishitani R, Sherrer RL, O’Donoghue P, Yuan J, Oshikane H, Domae N, Defranco J, S l D, Nureki O: Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation. Nucleic Acids Res 2008, 36:1187199. 48. Ganichkin OM, Xu XM, Carlson BA, Mix H, Hatfield DL, Gladyshev VN, Wahl MC: Structure and catalytic mechanism of eukaryotic selenocysteine synthase. J Biol Chem 2008, 283:5849865. 49. Palioura S, Sherrer RL, Steitz TA, S l D, Simonovic M: The human SepSecS-tRNASec complicated reveals the mechanism of selenocysteine formation. Science 2009, 325:32125. 50. Kernebeck T, Lohse AW, Gr zinger J: A bioinformatical method suggests the function in the autoimmune hepatitis target antigen soluble liver antigen/liver pancreas. Hepatology 2001, 34:23033. 51. Strettell MD, Donaldson PT, Thomson LJ, Santrach PJ, Moore SB, Czaja AJ, Williams R: Allelic basis for HLA-encoded susceptibility to form 1 autoimmune hepatitis. Gastroenterology 1997, 112:2028035. 52. Todd JA, Bell JI, McDevitt HO: HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987, 329:59904. 53. RenvoisA, Merhej V, Georgiades K, Raoult D: Intracellular Rickettsiales Insights into manipulators of eukaryotic cells. Trends Mol Med 2011, 17:57383.Astragaloside IV Biological Activity 54.Oleic acid custom synthesis Frykholm BO: On the query of infectious aetiologies for several sclerosis schizophrenia as well as the chronic fatigue syndrome and their remedy with antibiotics.PMID:23543429 Med Hypotheses 2009, 72:73639. 55. Emelyanov VV: Rickettsiaceae rickettsia-like endosymbionts plus the origin of mitochondria. Biosci Rep 2001, 21:17.doi:10.1186/1742-4682-10-25 Cite this short article as: Paiardini and Pascarella: Structural mimicry involving SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: insights from an in silico study. Theoretical Biology and Medical Modelling 2013 ten:25.
Secondary lymphoid organs (SLO) are internet sites of very organized lymphoid cell accumulation, supported by a network of strom.