Product Name: ABCG2 (CD338) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500
User Note:
Predicted Molecular Weight: 65 – 80 kDa
Immunogen: ABCG2 (CD338) antibody was raised against a peptide sequence around aa.160~164 ( R-I-N-R-V) derived from Human ABCG2 (CD338).
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 3546-41-6
Product: Pyrvinium pamoate
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481, MRX
Accession NO.: NP_004818.2
Protein Ino: 62526033
Official Symbol: ABCG2
Geneid: 9429
Background: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
PubMed ID:http://aac.asm.org/content/51/12/4249.abstract
