Product Name: a Synuclein (Ab 133) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IF, WB
Applications: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 18 kDa
Immunogen: a-Synuclein (Ab-133) antibody was raised against a peptide sequence around aa. 131~135 (E-G-Y-Q-D) derived from Human α-Synuclein.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 59-23-4
Product: D-Galactose
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: PD1, NACP, PARK1, PARK4, SYN, SYUA, alpha-synuclein
Accession NO.: NP_000336.1
Protein Ino: 4507109
Official Symbol: SNCA
Geneid: 6622
Background: May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
PubMed ID:http://aac.asm.org/content/51/11/4171.abstract
