Product Name: IL-22 Receptor Antibody
Species Reactivity: Human, Rat
Tested Applications: ELISA, WB
Applications: IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 1 μg/mL. An approximately 62 kDa band can be detected.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 62 kDa
Immunogen: IL-22 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human IL-22.The immunogen is located within the last 50 amino acids of IL-22 Receptor.
Host Species: Rabbit
Purification: IL-22 Receptor Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 53963-43-2
Product: Elbasvir
Buffer: IL-22 Receptor Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: IL-22 Receptor antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-22 Receptor Antibody: IL22R, CRF2-9, IL22R1, IL22R, Interleukin-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, IL-22 receptor subunit alpha-1
Accession NO.: AF286095
Protein Ino: 10719607
Official Symbol: IL22RA1
Geneid: 58985
Background: IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
PubMed ID:http://aac.asm.org/content/26/3/354.abstract
