Product Name: IL-17A Antibody [17-142F]
Species Reactivity: Human
Tested Applications: ELISA, Flow
Applications: ELISA: (direct and indirect: 1:500-1:5,000). Flow Cytometry: (1:20-1:500). Optimal conditions must be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant human IL-17A.
Host Species: Mouse
Purification:
Physical State: Liquid
CAS NO.: 6004-24-6
Product: VU0361737
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 0.5 mg/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8
Accession NO.: NP_002181
Protein Ino: 4504651
Official Symbol: IL17A
Geneid: 3605
Background: IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.
PubMed ID:http://aac.asm.org/content/26/2/155.abstract
