Product Name: IKK- gamma (phospho Ser31) Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 48 kDa
Immunogen: IKK- gamma (phospho Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine 31 (E-E-S (p)-P-L) derived from Human IKK-gamma.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 66309-69-1
Product: KS176
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: FIP-3, FIP3, I-kappa-B kinase gamma, IKBKG, IKKAP1
Accession NO.: NP_001093326.2
Protein Ino: 3641279
Official Symbol: IKBKG
Geneid: 8517
Background: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either Lys-63-linked or linear polyubiquitin) and its functional importance is reported conflictingly.
PubMed ID:http://aac.asm.org/content/25/6/781.abstract
