Product Name: IGF 1R (Ab 1161) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 200 95 kDa
Immunogen: IGF-1R (Ab-1161) antibody was raised against a peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 223652-90-2
Product: UNC1079
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IGFR, CD221, IGFIR, JTK13, MACS, PRKCSL, Insulin-like growth factor I receptor, IGF1R, kinase IGF1R
Accession NO.: NP_000866.1
Protein Ino: 4557665
Official Symbol: IGF1R
Geneid: 3480
Background: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
PubMed ID:http://aac.asm.org/content/25/3/398.abstract
