Product Name: HSPBP1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Hsp70-binding protein 1 antibody can be used for the detection of Hsp70-binding protein 1 by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 39.5 kDa (calculated)
Immunogen: 31-136
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 459168-41-3
Product: PD168393
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: HSPBP1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HSPBP, PP1845, Hsp70-binding protein 1, Heat shock protein-binding protein 1, HspBP1, Hsp70binding protein 1, Hsp70-interacting protein 1, Hsp70-binding protein 2, HspBP2, Hsp70-interacting protein 2
Accession NO.: NP_036399.2
Protein Ino: 21361407
Official Symbol: HSPBP1
Geneid: 23640
Background: FUNCTION: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.SUBUNIT: Interacts with the ATP-binding domain of HSPA1A. Detected in a ternary complex containing STUB1, HSPA1A and HSPBP1.SIMILARITY: Contains 4 ARM repeats.
PubMed ID:http://aac.asm.org/content/24/4/505.abstract
