Product Name :
anti-hdac6 rabbit mab
Isotype :
IgG
Conjugate :
Unconjugated
Synonyms:
Histone deacetylase 6, HD6, Tubulin-lysine deacetylase
UniProt ID :
Q9Z2V5
Immunogen:
MW (kDa) :
Specificity:
Purity :
Protein A purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. Diseases associated with HDAC6 include Chondrodysplasia with Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia and Brachydactyly. Among its related pathways are CREB Pathway and Signaling by NOTCH1. Gene Ontology (GO) annotations related to this gene include enzyme binding and ubiquitin protein ligase binding. Cellular location Cytoplasm, Cytoskeleton and Cell nucleus
Images :
WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: K562, 2: HCT-116Protein loading quantity: 20 μgExposure time: 60 sPredicted band size: 126 kDaObserved band size: 160 kDa IHC-P Tissue: Human kidneySection type: Formalin-fixed & Paraffin_x005f_x0002_embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:1000Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with
Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-HDAC6 Rabbit mAb Clone Number: JRMR-10770-54 Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB IHC-P Reactivity: Human, Mouse Synonyms: Histone deacetylase 6, HD6, Tubulin-lysine deacetylase Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms Histone deacetylase 6, HD6, Tubulin-lysine deacetylase UniProt ID Q9Z2V5 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:5000 Human IHC-P 1:200 – 1:1000 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. Diseases associated with HDAC6 include Chondrodysplasia with Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia and Brachydactyly. Among its related pathways are CREB Pathway and Signaling by NOTCH1. Gene Ontology (GO) annotations related to this gene include enzyme binding and ubiquitin protein ligase binding. Cellular location Cytoplasm, Cytoskeleton and Cell nucleus Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: K562, 2: HCT-116Protein loading quantity: 20 μgExposure time: 60 sPredicted band size: 126 kDaObserved band size: 160 kDa IHC-P Tissue: Human kidneySection type: Formalin-fixed & Paraffin_x005f_x0002_embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:1000Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with
Recombinant Rabbit Monoclonal Anti-HDAC6 Rabbit mAb Clone Number: JRMR-10770-54 Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB IHC-P Reactivity: Human, Mouse Synonyms: Histone deacetylase 6, HD6, Tubulin-lysine deacetylase Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms Histone deacetylase 6, HD6, Tubulin-lysine deacetylase UniProt ID Q9Z2V5 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:5000 Human IHC-P 1:200 – 1:1000 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. Diseases associated with HDAC6 include Chondrodysplasia with Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia and Brachydactyly. Among its related pathways are CREB Pathway and Signaling by NOTCH1. Gene Ontology (GO) annotations related to this gene include enzyme binding and ubiquitin protein ligase binding. Cellular location Cytoplasm, Cytoskeleton and Cell nucleus Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: K562, 2: HCT-116Protein loading quantity: 20 μgExposure time: 60 sPredicted band size: 126 kDaObserved band size: 160 kDa IHC-P Tissue: Human kidneySection type: Formalin-fixed & Paraffin_x005f_x0002_embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:1000Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with
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