Product Name :
VEGFR Tyrosine Kinase Inhibitor II
Description:
VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively).1 It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 µM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 µM).1 VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.
CAS:
269390-69-4
Molecular Weight:
337.80
Formula:
C19H16ClN3O
Chemical Name:
N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide
Smiles :
O=C(NC1C=CC(Cl)=CC=1)C1=CC=CC=C1NCC1=CC=NC=C1
InChiKey:
GGPZCOONYBPZEW-UHFFFAOYSA-N
InChi :
InChI=1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{BS3 Crosslinker} medchemexpress|{BS3 Crosslinker} ADC Linker|{BS3 Crosslinker} NF-κB|{BS3 Crosslinker} Purity & Documentation|{BS3 Crosslinker} References|{BS3 Crosslinker} supplier}
Shelf Life:
≥12 months if stored properly.{{Tecovirimat} MedChemExpress|{Tecovirimat} Orthopoxvirus|{Tecovirimat} Biological Activity|{Tecovirimat} References|{Tecovirimat} custom synthesis|{Tecovirimat} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively).PMID:24367939 1 It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 µM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 µM).1 VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.|Product information|CAS Number: 269390-69-4|Molecular Weight: 337.80|Formula: C19H16ClN3O|Chemical Name: N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide|Smiles: O=C(NC1C=CC(Cl)=CC=1)C1=CC=CC=C1NCC1=CC=NC=C1|InChiKey: GGPZCOONYBPZEW-UHFFFAOYSA-N|InChi: InChI=1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
