Product Name :
Loureirin A
Description:
Loureirin A is a flavonoid extracted from Dragon’s Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.
CAS:
119425-89-7
Molecular Weight:
286.32
Formula:
C17H18O4
Chemical Name:
3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one
Smiles :
COC1=CC=C(CCC(=O)C2C=CC(O)=CC=2)C(=C1)OC
InChiKey:
RSAIVLRELNGZEY-UHFFFAOYSA-N
InChi :
InChI=1S/C17H18O4/c1-20-15-9-5-13(17(11-15)21-2)6-10-16(19)12-3-7-14(18)8-4-12/h3-5,7-9,11,18H,6,10H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Terutroban} medchemexpress|{Terutroban} Prostaglandin Receptor|{Terutroban} Protocol|{Terutroban} References|{Terutroban} supplier|{Terutroban} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{sn-Glycerol 3-phosphate} medchemexpress|{sn-Glycerol 3-phosphate} Endogenous Metabolite|{sn-Glycerol 3-phosphate} Epigenetics|{sn-Glycerol 3-phosphate} Purity & Documentation|{sn-Glycerol 3-phosphate} In stock|{sn-Glycerol 3-phosphate} supplier}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24516446
Additional information:
Loureirin A is a flavonoid extracted from Dragon’s Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.|Product information|CAS Number: 119425-89-7|Molecular Weight: 286.32|Formula: C17H18O4|Chemical Name: 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one|Smiles: COC1=CC=C(CCC(=O)C2C=CC(O)=CC=2)C(=C1)OC|InChiKey: RSAIVLRELNGZEY-UHFFFAOYSA-N|InChi: InChI=1S/C17H18O4/c1-20-15-9-5-13(17(11-15)21-2)6-10-16(19)12-3-7-14(18)8-4-12/h3-5,7-9,11,18H,6,10H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 86.6 mg/mL (302.46 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM.|Products are for research use only. Not for human use.|
