anti-csf-1r rabbit mab

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Recombinant Rabbit Monoclonal Anti-CSF-1R Rabbit mAb Clone Number: JRMR-227 Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P Reactivity: Human, Mouse Synonyms: CSF-1R, M-CSF-R, CD115, CSF1R, FMS, Csfmr Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CSF-1R, M-CSF-R, CD115, CSF1R, FMS, Csfmr UniProt ID P07333 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:500 – 1:2000 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Cellular location Membrane Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: RAW264.7, 2: Mouse placenta, 3: Rat lungProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 109 kDaObserved band size: 109 kDa ICC/IF Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: RAW264.7, 2: Mouse placenta, 3: Rat lungProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 109 kDaObserved band size: 109 kDa :
Recombinant Rabbit Monoclonal Anti-CSF-1R Rabbit mAb Clone Number: JRMR-227 Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P Reactivity: Human, Mouse Synonyms: CSF-1R, M-CSF-R, CD115, CSF1R, FMS, Csfmr Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CSF-1R, M-CSF-R, CD115, CSF1R, FMS, Csfmr UniProt ID P07333 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:500 – 1:2000 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Cellular location Membrane Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: RAW264.7, 2: Mouse placenta, 3: Rat lungProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 109 kDaObserved band size: 109 kDa ICC/IF Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:5000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: RAW264.7, 2: Mouse placenta, 3: Rat lungProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 109 kDaObserved band size: 109 kDa