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Product Name :
anti-claudin-18.2 rabbit mab

Isotype :
IgG

Conjugate :
Unconjugated

Synonyms:
CLDN18, Claudin 18.2

UniProt ID :
P56856

Immunogen:

MW (kDa) :

Specificity:

Purity :
Protein A purified

Purity :
PBS, Glycerol, BSA

Storage :
Store at -20°C. Avoid freeze/thaw cycles.

Stability:
Stable for 12 months from date of receipt/reconstitution.

Background :
Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm. Cellular location Membrane

Images :
IHC-P Tissue: Human stomach Section type: Formalin-fixed & Paraffin-embeddedsection Retrieval method: High temperature and highpressureRetrieval buffer: Tris/EDTA buffer, pH9.0Primary Ab dilution: 1:1000 Primary Ab incubation condition: 1 hour at roomtemperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP(Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with

Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-Claudin-18.2 Rabbit mAb Clone Number: JRMR-10449(2)-43 Host: Rabbit Clonality: Recombinant Monoclonal Applications: IHC-P Reactivity: Human, Mouse, Rat Synonyms: CLDN18, Claudin 18.2 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CLDN18, Claudin 18.2 UniProt ID P56856 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:200 – 1:1000 Human, Mouse, Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm. Cellular location Membrane Images IHC-P Tissue: Human stomach Section type: Formalin-fixed & Paraffin-embeddedsection Retrieval method: High temperature and highpressureRetrieval buffer: Tris/EDTA buffer, pH9.0Primary Ab dilution: 1:1000 Primary Ab incubation condition: 1 hour at roomtemperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP(Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with :

Recombinant Rabbit Monoclonal Anti-Claudin-18.2 Rabbit mAb Clone Number: JRMR-10449(2)-43 Host: Rabbit Clonality: Recombinant Monoclonal Applications: IHC-P Reactivity: Human, Mouse, Rat Synonyms: CLDN18, Claudin 18.2 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CLDN18, Claudin 18.2 UniProt ID P56856 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:200 – 1:1000 Human, Mouse, Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm. Cellular location Membrane Images IHC-P Tissue: Human stomach Section type: Formalin-fixed & Paraffin-embeddedsection Retrieval method: High temperature and highpressureRetrieval buffer: Tris/EDTA buffer, pH9.0Primary Ab dilution: 1:1000 Primary Ab incubation condition: 1 hour at roomtemperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP(Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Betaine hydrochloride