anti-cdcp1 mouse mab

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Recombinant Anti-CDCP1 Mouse mAb Clone Number: 12160 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: SIMA135, CD318, TRASK Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms SIMA135, CD318, TRASK UniProt ID Q9H5V8 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background CD318 is a 140 kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD). CD318 is cleaved by serine proteases at the extracellular domain next to Arg368 to generate a truncated molecule of 80 kDa size. Different cell lines express different amounts of p140 and p80, depending on the activity of endogenous serine proteases. In vivo, CD318 is not cleaved during normal physiological circumstances, but its cleavage can be induced during tumorigenesis or tissue injury. Besides, may be involved in cell adhesion and cell matrix association and play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. Cellular location Membrane, Secreted Images FC Cell line: HT-29 Fixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgG Unlabeled control: Cells without incubation with primary and secondary antibodies (Black line). Isotype control: Mouse monoclonal IgG2b (Blue line). Description: Line red is the positive signal for :
Recombinant Anti-CDCP1 Mouse mAb Clone Number: 12160 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: SIMA135, CD318, TRASK Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms SIMA135, CD318, TRASK UniProt ID Q9H5V8 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background CD318 is a 140 kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD). CD318 is cleaved by serine proteases at the extracellular domain next to Arg368 to generate a truncated molecule of 80 kDa size. Different cell lines express different amounts of p140 and p80, depending on the activity of endogenous serine proteases. In vivo, CD318 is not cleaved during normal physiological circumstances, but its cleavage can be induced during tumorigenesis or tissue injury. Besides, may be involved in cell adhesion and cell matrix association and play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis. Cellular location Membrane, Secreted Images FC Cell line: HT-29 Fixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgG Unlabeled control: Cells without incubation with primary and secondary antibodies (Black line). Isotype control: Mouse monoclonal IgG2b (Blue line). Description: Line red is the positive signal for