anti-cd161 mouse mab

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Recombinant Anti-CD161 Mouse mAb Clone Number: 11060 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: KLRB1, CLEC5B, NKRP1A Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms KLRB1, CLEC5B, NKRP1A UniProt ID Q12918 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alphaGal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. Cellular location Membrane Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGIsotype control: Mouse monoclonal IgG1 (Image A). Description: Q4 quadrant in Image B is the positive signal for :
Recombinant Anti-CD161 Mouse mAb Clone Number: 11060 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: KLRB1, CLEC5B, NKRP1A Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms KLRB1, CLEC5B, NKRP1A UniProt ID Q12918 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alphaGal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. Cellular location Membrane Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGIsotype control: Mouse monoclonal IgG1 (Image A). Description: Q4 quadrant in Image B is the positive signal for