Share this post on:

Product Name :
anti-sigirr rabbit mab

Isotype :
IgG

Conjugate :
Unconjugated

Synonyms:
TIR8

UniProt ID :
Q9JLZ8

Immunogen:

MW (kDa) :

Specificity:

Purity :
Protein A purified

Purity :
PBS, Glycerol, BSA

Storage :
Store at -20°C. Avoid freeze/thaw cycles.

Stability:
Stable for 12 months from date of receipt/reconstitution.

Background :
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. Cellular location Membrane

Images :
WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:1000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: Mouse kidney, 2: Mouse stomachProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 46 kDaObserved band size: 80 kDa

Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-SIGIRR Rabbit mAb Clone Number: JRMR-10416-41 Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB Reactivity: Mouse Synonyms: TIR8 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms TIR8 UniProt ID Q9JLZ8 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. Cellular location Membrane Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:1000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: Mouse kidney, 2: Mouse stomachProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 46 kDaObserved band size: 80 kDa :

Recombinant Rabbit Monoclonal Anti-SIGIRR Rabbit mAb Clone Number: JRMR-10416-41 Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB Reactivity: Mouse Synonyms: TIR8 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms TIR8 UniProt ID Q9JLZ8 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. Cellular location Membrane Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:1000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: Mouse kidney, 2: Mouse stomachProtein loading quantity: 20 μgExposure time: 60 sPredicted band size: 46 kDaObserved band size: 80 kDa

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
IL-6 Antibody (YA724)
Iba1 Antibody
Thrombomodulin Antibody (YA891): Thrombomodulin Antibody (YA891) is an unconjugated, approximately 95 kDa, rabbit-derived, anti-Thrombomodulin (YA891) monoclonal antibody. Thrombomodulin Antibody (YA891) can be used for: WB, ICC/IF, IP expriments in human background without labeling.

Share this post on:

Author: Betaine hydrochloride