anti-agk mouse mab

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Recombinant Anti-AGK Mouse mAb Clone Number: JMMR-3556 Host: Mouse Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human Synonyms: Acylglycerol kinase, HsMuLK, Multi-substrate lipid kinase, MULK Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms Acylglycerol kinase, HsMuLK, Multi-substrate lipid kinase, MULK UniProt ID Q53H12 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Acylglycerol kinase (AGK) is a mitochondrial lipid kinase that phosphorylates monoacylglycerol and diacylglycerol to generate bioactive phospholipids lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Research studies show that the kinase activity of AGK is required for the activation of PI3K-mTOR signaling and the subsequent enhancement of glycolysis in activated CD8+ T cells. AGK is therefore essential for the growth, proliferation and antitumor function of activated CD8+T cells. In addition, AGK is also a subunit of the mitochondrial TIM22 protein import complex independent of its kinase activity. AGK is critical for the stabilization of the TIM22 complex. Cellular location Mitochondrion Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Mouse IgGH&L(HRP Conjugate) Lysate: 1: A431, 2: NCI-H1299, 3: 293T Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 47 kDa Observed band size: 47 kDa :
Recombinant Anti-AGK Mouse mAb Clone Number: JMMR-3556 Host: Mouse Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human Synonyms: Acylglycerol kinase, HsMuLK, Multi-substrate lipid kinase, MULK Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms Acylglycerol kinase, HsMuLK, Multi-substrate lipid kinase, MULK UniProt ID Q53H12 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Acylglycerol kinase (AGK) is a mitochondrial lipid kinase that phosphorylates monoacylglycerol and diacylglycerol to generate bioactive phospholipids lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Research studies show that the kinase activity of AGK is required for the activation of PI3K-mTOR signaling and the subsequent enhancement of glycolysis in activated CD8+ T cells. AGK is therefore essential for the growth, proliferation and antitumor function of activated CD8+T cells. In addition, AGK is also a subunit of the mitochondrial TIM22 protein import complex independent of its kinase activity. AGK is critical for the stabilization of the TIM22 complex. Cellular location Mitochondrion Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Mouse IgGH&L(HRP Conjugate) Lysate: 1: A431, 2: NCI-H1299, 3: 293T Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 47 kDa Observed band size: 47 kDa