anti-ldl receptor rabbit mab

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Recombinant Rabbit Monoclonal Anti-LDL Receptor Rabbit mAb Clone Number: JRMR-10562 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB IHC-P FC Reactivity: Human Synonyms: LDLR Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms LDLR UniProt ID P01130 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human IHC-P 1:200 – 1:1000 Human FC 1:50 – 1:100 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background LDL receptor is a transmembrane protein, which binds LDL (low-density lipoprotein), the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. The complexes recycle through the endocytic pathway. Variants affecting this gene cause familial hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum LDL cholesterol levels. Besides, LDLR also acts as a receptor for hepatitis C virus in hepatocytes and vesicular stomatitis virus. Cellular location Membrane, Golgi apparatus, Endosome, Lysosome Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:1000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: HeLa, 2: HepG2Protein loading quantity: 20 μgExposure time: 60 sPredicted band size: 95 kDaObserved band size: 140 kDa IHC-P Tissue: Human liver cancerSection type: Formalin-fixed & Paraffin_x005f_x0002_embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:1000Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with :
Recombinant Rabbit Monoclonal Anti-LDL Receptor Rabbit mAb Clone Number: JRMR-10562 Host: Rabbit Clonality: Recombinant Monoclonal Applications： WB IHC-P FC Reactivity: Human Synonyms: LDLR Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms LDLR UniProt ID P01130 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human IHC-P 1:200 – 1:1000 Human FC 1:50 – 1:100 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background LDL receptor is a transmembrane protein, which binds LDL (low-density lipoprotein), the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. The complexes recycle through the endocytic pathway. Variants affecting this gene cause familial hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum LDL cholesterol levels. Besides, LDLR also acts as a receptor for hepatitis C virus in hepatocytes and vesicular stomatitis virus. Cellular location Membrane, Golgi apparatus, Endosome, Lysosome Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:1000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: 1: HeLa, 2: HepG2Protein loading quantity: 20 μgExposure time: 60 sPredicted band size: 95 kDaObserved band size: 140 kDa IHC-P Tissue: Human liver cancerSection type: Formalin-fixed & Paraffin_x005f_x0002_embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:1000Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with