Product Name :
anti-irg1 rabbit pab
Isotype :
IgG
Conjugate :
Unconjugated
Synonyms:
CAD, Aconitate decarboxylase, Immune-responsive gene 1 protein, Cis-aconitic acid decarboxylase, ACOD1
UniProt ID :
A6NK06
Immunogen:
MW (kDa) :
Specificity:
Purity :
Protein A purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions. It is also highly expressed in the pregnant uterus during implantation. IRG1 is a cis-aconitate decarboxylase that produces itaconic acid by decarboxylating cis-aconitic acid, an intermediate of the tricarboxylic acid cycle. Itaconic acid is an endogenous inhibitor of succinate dehydrogenase, linking macrophage metabolic rewiring and regulation of inflammation. Cellular location Mitochondrion
Images :
WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:10000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: Raw264.7+LPS (100 ng/ml, 4 hours) (-) (+)Protein loading quantity: 20 μgExposure time: 30 sPredicted band size: 53 kDaObserved band size: 53 kDa
Vapor Pressure :
Anti-IRG1 Rabbit pAb Clone Number: / Host: Rabbit Clonality: Polyclonal Applications： WB Reactivity: Mouse Synonyms: CAD, Aconitate decarboxylase, Immune-responsive gene 1 protein, Cis-aconitic acid decarboxylase, ACOD1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CAD, Aconitate decarboxylase, Immune-responsive gene 1 protein, Cis-aconitic acid decarboxylase, ACOD1 UniProt ID A6NK06 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:2000-1:10000 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions. It is also highly expressed in the pregnant uterus during implantation. IRG1 is a cis-aconitate decarboxylase that produces itaconic acid by decarboxylating cis-aconitic acid, an intermediate of the tricarboxylic acid cycle. Itaconic acid is an endogenous inhibitor of succinate dehydrogenase, linking macrophage metabolic rewiring and regulation of inflammation. Cellular location Mitochondrion Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:10000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: Raw264.7+LPS (100 ng/ml, 4 hours) (-) (+)Protein loading quantity: 20 μgExposure time: 30 sPredicted band size: 53 kDaObserved band size: 53 kDa
Anti-IRG1 Rabbit pAb Clone Number: / Host: Rabbit Clonality: Polyclonal Applications： WB Reactivity: Mouse Synonyms: CAD, Aconitate decarboxylase, Immune-responsive gene 1 protein, Cis-aconitic acid decarboxylase, ACOD1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms CAD, Aconitate decarboxylase, Immune-responsive gene 1 protein, Cis-aconitic acid decarboxylase, ACOD1 UniProt ID A6NK06 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:2000-1:10000 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions. It is also highly expressed in the pregnant uterus during implantation. IRG1 is a cis-aconitate decarboxylase that produces itaconic acid by decarboxylating cis-aconitic acid, an intermediate of the tricarboxylic acid cycle. Itaconic acid is an endogenous inhibitor of succinate dehydrogenase, linking macrophage metabolic rewiring and regulation of inflammation. Cellular location Mitochondrion Images WB Blocking buffer: 5% NFDM/TBSTPrimary Ab dilution: 1:10000Primary Ab incubation condition: 2 hours at room temperatureSecondary Ab: Goat Anti-Rabbit IgG H&L pAb (HRP Conjugate)Lysate: Raw264.7+LPS (100 ng/ml, 4 hours) (-) (+)Protein loading quantity: 20 μgExposure time: 30 sPredicted band size: 53 kDaObserved band size: 53 kDa
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