Mean annual temperature and temperature of July were shown for all climate stations in Astrakhan, Volgograd, Krasnodar and Rostov-on-Don. The average annual trend from the imply temperature in July for 1961010 ranged from 0.02 C/year (p 0.01) to 0.09 C/year (p 0.001) in numerous cities, demonstrating a rise in summer temperature everywhere. The number of exceptionally hot days in each and every on the studied cities varied from 10 to 37 per year. In comparison with 1961990, inside the subsequent 10 years the amount of extremely hot days in Melitracen Data Sheet Volgograd increased by three occasions, in Krasnodar–by 1 and also a half times; in Rostov-on-Don the increase was not substantial. In these cities, the influence of 22 brief (lasting five days) and 19 long (lasting eight days or more) heat waves on the mortality was estimated. The strongest heat wave of 2010,Atmosphere 2021, 12,9 ofmanifested in all cities, was excluded from the study. Additional mortality per one hundred thousand people today through heat waves was: 7.six (95 CI: six.7.five) in Volgograd, eight.1 (95 CI: 7.two.9) in Rostov-on-Don, 8.five (95 CI: 7.5.six) in Krasnodar and ten.eight (95 CI: 9.32.two) in Astrakhan. The highest risk in Astrakhan was explained by the record quantity of lengthy heat waves. A meta-analysis of risk in 4 southern cities showed statistically important results of a combined threat assessment for 15 mortality indicators. The biggest number of extra deaths was detected in Volgograd and in Rostov-on-Don for the duration of days when the temperature exceeded the specified heat threshold [97]. On top of that for mortality in Rostov-on-Don through the period from 1999 to 2011, excluding the heat wave of 2010, boost in mortality from coronary heart illness cerebrovascular illnesses was shown, making use of air temperature (T), AT, HUM and PET as climate parameters [110]. Equivalent for the study in Moscow, an abnormal wave of 21 days duration in Rostov-on-Don in summer time of 2010 was excluded in the sample. The study demonstrated that T and PET were the ideal predictors for mortality from coronary heart illness in the age of 304 years (RR = 1.19 (95 CI: 0.09.21); PET for mortality from cerebrovascular diseases at the age of 304 years (1.64 (95 CI: 0.18.43) having a two day lag; PET–for elderly with coronary heart disease (1.51 (95 CI: 0.09.03) with a 3 day lag, and with cerebrovascular illnesses (1.72 (95 CI: 0.058.63) using a 1 day lag [110]. A comparison of the outcomes of assessing excess mortality throughout heat waves in southern in European Russia and Bromfenac Inhibitor northern cities within the Arctic area showed additional substantial effect of hot extremes in southern cities. The relative raise in mortality from cerebrovascular illnesses at the age of 65+ for the duration of heat waves was 66 (95 CI: 548) in southern cities in comparison to 35 (95 CI: 137) in northern cities, i.e., the relative increase in the south was nearly twice as high as in the north [97]. The doable explanation may very well be the variations in demographical structure on the population in these regions: by the age 65, persons with potentially really serious health issues alter their permanent place of residence, migrating from north to south, thereby escalating the threat of mortality in southern cities [192]. three.4. Siberia, Continental Climate The temperature thresholds for hot extremes in two cities of the Western Siberia (Barnaul and Kemerovo) and in four cities in the Eastern Siberia (Bratsk, Chita, Krasnoyarsk, Irkutsk) for the study period from 1999 to 2015 were homogeneous, varying in a narrow range from 21 to 23 C [98].