Product Name: IL-36RN Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IF, IHC-P, WB
Applications: IL-36RN antibody can be used for detection of IL-36RN by Western blot at 1 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Observed Molecular Weight: 24 kDa
Immunogen: IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN.The immunogen is located within the last 50 amino acids of IL-36RN.
Host Species: Rabbit
Purification: IL-36RN antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 34444-01-4
Product: beta-Mangostin
Buffer: IL-36RN antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-36RN antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-36RN Antibody: FIL1, FIL1D, IL1F5, IL1L1, PSORP, IL1HY1, IL1RP3, IL36RA, FIL1(DELTA), UNQ1896/PRO4342, Interleukin-36 receptor antagonist protein, FIL1 delta, IL-1RP3
Accession NO.: NP_775262
Protein Ino: 27894310
Official Symbol: IL36RN
Geneid: 26525
Background: IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).
PubMed ID:http://aac.asm.org/content/26/4/481.abstract
