Product Name: IL-36G Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: IL-36G antibody can be used for detection of IL-36G by Western blot at 1 – 2 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 19 kDa Observed: 22 kDa
Immunogen: IL-36G antibody was raised against a 13 amino acid peptide near the carboxy terminus of human IL-36G.The immunogen is located within the last 50 amino acids of IL-36G.
Host Species: Rabbit
Purification: IL-36G antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 345909-26-4
Product: Coixol
Buffer: IL-36G antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-36G antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-36G Antibody: IL1E, IL1F9, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2, IL1E, UNQ2456/PRO5737, Interleukin-36 gamma, IL-1-related protein 2
Accession NO.: NP_062564
Protein Ino: 9665234
Official Symbol: IL36G
Geneid: 56300
Background: IL-36G is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36G is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36B, IL-36G requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). IL-36G expression is stimulated by interferon-gamma, tumor necrosis factor-alpha and interleukin 1 (4). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (5).
PubMed ID:http://aac.asm.org/content/26/4/476.abstract
