Product Name: IL-32 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: IL-32 antibody can be used for the detection of IL-32 by Western blot at 5 – 10 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: IL-32 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human IL-32.The immunogen is located within the last 50 amino acids of IL-32.
Host Species: Rabbit
Purification: IL-32 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 906-33-2
Product: Chlorphenoxamine
Buffer: IL-32 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-32 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-32 Antibody: NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, IL-32beta, IL-32alpha, IL-32delta, IL-32gamma, NK4, Interleukin-32, Natural killer cells protein 4, IL-32
Accession NO.: AAH09401
Protein Ino: 14424787
Official Symbol: IL32
Geneid: 9235
Background: IL-32 Antibody: Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-α, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNγ, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
PubMed ID:http://aac.asm.org/content/26/3/424.abstract
