Product Name: IL-28B Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, WB
Applications: IL-28B antibody can be used for detection of IL-28B by Western blot at 1 – 2 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 20 kDa Observed: 16kDa
Immunogen: IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B.The immunogen is located within amino acids 120 – 170 of IL-28B .
Host Species: Rabbit
Purification: IL-28B Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 80681-45-4
Product: GBT 440
Buffer: IL-28B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-28B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-28B Antibody : IL28B, IL28C, IL-28B, IL28B, ZCYTO22, Interferon lambda-3, Cytokine Zcyto22, IFN-lambda-3
Accession NO.: NP_742151
Protein Ino: 28144901
Official Symbol: IFNL3
Geneid: 282617
Background: Interleukin 28 (IL-28B), also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1). The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2,3). All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1).
PubMed ID:http://aac.asm.org/content/26/3/408.abstract
