Product Name: IL-22 Antibody
Species Reactivity: Mouse
Tested Applications: ELISA, WB
Applications: ELISA:Direct:To detect mIL-22 by indirect ELISA (using 100 μL/well antibody solution) a concentration of 0.5 – 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 – 0.4 ng/well of recombinant mIL-22.SandwichTo detect mIL-22 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 – 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Murine IL-22 as a detection antibody, allows the detection of at least 0.2 – 0.4 ng/well of recombinant mIL-22. Western Blot:To detect mIL-22 by Western Blot analysis this antibody can be used at a concentration of 0.1 – 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-22 is 1.5 – 3.0 ng/lane, under either reducing or non-reducing conditions.
User Note: Centrifuge vial prior to opening.
Predicted Molecular Weight:
Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-22. Murine IL-22 specific antibody was purified by affinity chromatography employing immobilized mIL-22 matrix.
Host Species: Rabbit
Purification:
Physical State: Lyophilized
CAS NO.: 52286-74-5
Product: Ombitasvir
Buffer:
Concentration:
Storage Conditions: IL-22 antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-22, Iltif, IL-22a, ILTIFa, Il22a, Iltifa, Interleukin-22, IL-10-related T-cell-derived-inducible factor, IL-22
Accession NO.: Q9JJY9
Protein Ino: 17366895
Official Symbol: Il22
Geneid: 50929
Background: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
PubMed ID:http://aac.asm.org/content/26/3/347.abstract
