Product Name: IL-21 Antibody
Species Reactivity: Human
Tested Applications: ELISA, ICC, WB
Applications: IL-21 antibody can be used for detection of IL-21 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 18 kDa Observed: 18 kDa
Immunogen: IL-21 antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor.The immunogen is located within the last 50 amino acids of IL-21.
Host Species: Rabbit
Purification: IL-21 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 105558-26-7
Product: Mephenesin
Buffer: IL-21 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: IL-21 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-21 Antibody: Za11, IL-21, Interleukin-21, Za11
Accession NO.: NP_068575
Protein Ino: 11141875
Official Symbol: IL21
Geneid: 59067
Background: IL-21 Antibody: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
PubMed ID:http://aac.asm.org/content/26/3/335.abstract
