Product Name: IL-1a Antibody [1F3B3]
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: Western Blot:1:500 – 1,000ELISA:Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified recombinant human IL-1α expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification:
Physical State:
CAS NO.: 42540-40-9
Product: CCT251545
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration:
Storage Conditions: IL-1a monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: IL1F1, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA
Accession NO.: P01583
Protein Ino: 124297
Official Symbol: IL1A
Geneid: 3552
Background: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimers disease.
PubMed ID:http://aac.asm.org/content/26/2/256.abstract
