Product Name: IL-1F10 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC-P, WB
Applications: IL-1F10 antibody can be used for detection of IL-1F10 by Western blot at 1 – 2 μg/ml
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 17 kDa Observed: 20 kDa
Immunogen: IL-1F10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human IL-1F10.The immunogen is located within the last 50 amino acids of IL-1F10.
Host Species: Rabbit
Purification: IL-1F10 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 3902-71-4
Product: Ribocil-C
Buffer: IL-1F10 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-1F10 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-1F10 Antibody: IL-38, FKSG75, IL1HY2, IL-1HY2, IL1-theta, FIL1-theta, FIL1T, IL38, UNQ6119/PRO20041, Interleukin-1 family member 10, Family of interleukin 1-theta, IL-1F10
Accession NO.: NP_775184
Protein Ino: 27894307
Official Symbol: IL1F10
Geneid: 84639
Background: The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).
PubMed ID:http://aac.asm.org/content/26/2/272.abstract
