Product Name: IL-17RE Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: IL-17RE antibody can be used for detection of IL-17RE by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 78 kDa
Immunogen: Rabbit polyclonal IL-17RE antibody was raised against a 16 amino acid peptide near the center of human IL-17RE.The immunogen is located within amino acids 230 – 280 of IL-17RE.
Host Species: Rabbit
Purification: IL-17RE Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 483-63-6
Product: Sudan I
Buffer: IL-17RE Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-17RE antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-17RE Antibody: Interleukin-17 receptor E, IL-17 receptor E
Accession NO.: NP_705616
Protein Ino: 301129232
Official Symbol: IL17RE
Geneid: 132014
Background: IL-17RE Antibody: The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
PubMed ID:http://aac.asm.org/content/26/2/214.abstract
