Product Name: IGF2R (phospho Ser2409) Antibody
Species Reactivity: Human, Mouse
Tested Applications: IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
User Note:
Predicted Molecular Weight: 300 kDa
Immunogen: IGF2R (phospho Ser2409) antibody was raised against a peptide sequence around phosphorylation site of Serine 2409 (Q-D-S (p)-E-D) derived from Human IGF2R.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 103404-75-7
Product: Bax inhibitor peptide V5
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CI-MPR, CI-MPR, MPR300, MPRI
Accession NO.: NP_000867.2
Protein Ino: 317373416
Official Symbol: IGF2R
Geneid: 3482
Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
PubMed ID:http://aac.asm.org/content/25/4/518.abstract
