Product Name: IFIT1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: IFIT1 antibody can be used for detection of IFIT1 by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 53 kDa Observed: 53 kDa
Immunogen: IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1.The immunogen is located within amino acids 290 – 340 of IFIT1.
Host Species: Rabbit
Purification: IFIT1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 66-84-2
Product: Methoxatin (disodium salt)
Buffer: IFIT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IFIT1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IFIT1 Antibody: C56, P56, G10P1, IFI56, ISG56, IFI-56, IFIT-1, IFNAI1, RNM561, IFI-56K, Interferon-induced protein with tetratricopeptide repeats 1, Interferon-induced 56 kDa protein
Accession NO.: NP_001539
Protein Ino: 116534937
Official Symbol: IFIT1
Geneid: 3434
Background: The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).
PubMed ID:http://aac.asm.org/content/25/2/173.abstract
