Product Name: ICAM 1 (Ab 512) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 92 kDa
Immunogen: ICAM-1 (Ab-512) antibody was raised against a peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 110505-75-4
Product: RSL3 (1S,3R-)
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BB2, CD54, P3.58, ICA1, ICAM1
Accession NO.: NP_000192.2
Protein Ino: 167466198
Official Symbol: ICAM1
Geneid: 3383
Background: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
PubMed ID:http://aac.asm.org/content/24/6/925.abstract
