Product Name: ICAM3 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 60 kDa
Immunogen: This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the Central region of human ICAM3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 5108-96-3
Product: EPZ015866
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.37 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Accession NO.: P32942
Protein Ino: 206729872
Official Symbol: ICAM3
Geneid: 3385
Background: The protein encoded by this gene is a member of theintercellular adhesion molecule (ICAM) family. All ICAM proteinsare type I transmembrane glycoproteins, contain 2-9immunoglobulin-like C2-type domains, and bind to the leukocyteadhesion LFA-1 protein. This protein is constitutively andabundantly expressed by all leucocytes and may be the mostimportant ligand for LFA-1 in the initiation of the immuneresponse. It functions not only as an adhesion molecule, but alsoas a potent signalling molecule.
PubMed ID:http://aac.asm.org/content/25/1/7.abstract
