Product Name: Huntington Protein Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC, WB
Applications: ELISA, Western (immuno) blotting, Immunostaining (in testing)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: A synthetic peptide corresponding to the N-terminus.
Host Species: Rabbit
Purification: Affinity Purified
Physical State:
CAS NO.: 1626387-80-1
Product: NKL 22
Buffer:
Concentration:
Storage Conditions:
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HD, IT15, HD
Accession NO.: AAB38240
Protein Ino: 296434520
Official Symbol: HTT
Geneid: 3064
Background: Huntingtons disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington’s disease protein is ~350 kDa in size and is localized in the brain.
PubMed ID:http://aac.asm.org/content/24/5/750.abstract
