Product Name: HTRA3 Antibody
Species Reactivity: Gibbon, Human, Monkey, Rat
Tested Applications: IHC, WB
Applications: HTRA3 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 15 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: HTRA3 antibody was raised against amino acids 250 – 300 of HTRA3 (Human).
Host Species: Rabbit
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 18524-94-2
Product: GSK481
Buffer: PBS, 0.2% gelatin, 0.05% sodium azide.
Concentration:
Storage Conditions: HTRA3 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HTRA3, HtrA serine peptidase 3, Serine protease HTRA3, Tasp, Probable serine protease HTRA3, PRSP
Accession NO.: P83110
Protein Ino: 21542412
Official Symbol: HTRA3
Geneid: 94031
Background: HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. It is also called pregnancy-related serine protease. HtrA3 has two isoforms (long and short), which is produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-β proteins and inhibited the signaling of BMP-4, -2 and TGF-β 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurred upstream of the cell surface receptor.
PubMed ID:http://aac.asm.org/content/24/5/702.abstract
