Product Name: HTR3E Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: HTR3E antibody can be used for detection of HTR3E by ELISA at 1:312500. HTR3E antibody can be used for detection of HTR3E by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 53 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3E.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 56287-74-2
Product: E4CPG
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3E antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HTR3E, 5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E
Accession NO.: NP_872395
Protein Ino: 47519913
Official Symbol: HTR3E
Geneid: 285242
Background: HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
PubMed ID:http://aac.asm.org/content/24/5/679.abstract
