Product Name: HTR3A Antibody
Species Reactivity:
Tested Applications:
Applications: HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 55 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1380424-42-9
Product: ALS-8176
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Accession NO.: NP_000860
Protein Ino: 253735700
Official Symbol: HTR3A
Geneid: 3359
Background: HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
PubMed ID:http://aac.asm.org/content/24/5/663.abstract
