Product Name: HSD17B6 Antibody
Species Reactivity: Dog, Human, Mouse
Tested Applications: ELISA, IHC, WB
Applications: HSD17B6 antibody can be used for detection of HSD17B6 by ELISA at 1:62500. HSD17B6 antibody can be used for detection of HSD17B6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 35 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD17B6.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 19666-30-9
Product: Benzophenonetetracarboxylic acid
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HSD17B6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HSD17B6, HSE, RODH, SDR9C6
Accession NO.: NP_003716
Protein Ino: 19743808
Official Symbol: HSD17B6
Geneid: 8630
Background: HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
PubMed ID:http://aac.asm.org/content/24/1/104.abstract
