Product Name: HS2ST1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 42 kDa
Immunogen: This HS2ST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human HS2ST1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 537034-17-6
Product: MNS
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Heparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST, 282-, HS2ST1, HS2ST, KIAA0448
Accession NO.: Q7LGA3
Protein Ino: 68052326
Official Symbol: HS2ST1
Geneid: 9653
Background: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
PubMed ID:http://aac.asm.org/content/23/6/944.abstract
