Product Name: HRAS Antibody
Species Reactivity: Mouse, Rat
Tested Applications: WB
Applications: GTPase HRas antibody can be used for the detection of GTPase HRas by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 21.3 kDa (calculated)
Immunogen: 116-189
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 1383716-33-3
Product: Nanchangmycin
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: HRAS antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HRAS1, GTPase HRas, H-Ras-1, CTLO, HAMSV, HRAS1, K-RAS, N-RAS, RASH1, C-H-RAS, H-RASIDX, C-BAS/HAS, C-HA-RAS1, Transforming protein p21, c-H-ras
Accession NO.: NP_005334.1
Protein Ino: 4885425
Official Symbol: HRAS
Geneid: 3265
Background: FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.DISEASE: Defects in HRAS are also the cause of oral squamous cell carcinomas (OSCC).PTM: Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.SIMILARITY: Belongs to the small GTPase superfamily. Ras family.ENZYME REGULATION: Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
PubMed ID:http://aac.asm.org/content/23/6/857.abstract
