Product Name: HOPX Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: HOPX antibody can be used for detection of HOPX by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 12 kDa Observed: 18 kDa
Immunogen: HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX.The immunogen is located within the first 50 amino acids of HOPX.
Host Species: Rabbit
Purification: HOPX antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1446321-46-5
Product: D-3263 (hydrochloride)
Buffer: HOPX antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: HOPX antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HOP homeobox, homeodomain-only protein, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO
Accession NO.: NP_001138932
Protein Ino: 224451025
Official Symbol: HOPX
Geneid: 84525
Background: HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).
PubMed ID:http://aac.asm.org/content/23/4/555.abstract
